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Robert G Schaub Selected Research

2- (4- chlorobenzyl)- 3- hydroxy- 7,8,9,10- tetrahydrobenzo(H)quinoline- 4- carboxylic acid

2/2008Characterization of the novel P-selectin inhibitor PSI-697 [2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] quinoline-4-carboxylic acid] in vitro and in rodent models of vascular inflammation and thrombosis.
3/2007Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation.
9/2006Treatment with an oral small molecule inhibitor of P selectin (PSI-697) decreases vein wall injury in a rat stenosis model of venous thrombosis.
8/2005Decreased venous thrombosis with an oral inhibitor of P selectin.

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Robert G Schaub Research Topics

Disease

13Thrombosis (Thrombus)
04/2015 - 11/2002
10Venous Thrombosis (Deep-Vein Thrombosis)
04/2015 - 11/2002
6Hemophilia A (Haemophilia)
01/2014 - 06/2002
5Hemorrhage
05/2011 - 12/2003
5Inflammation (Inflammations)
04/2010 - 06/2004
3Pathologic Constriction (Stenosis)
04/2008 - 06/2004
2Fibrosis (Cirrhosis)
04/2015 - 11/2002
2Coronary Artery Disease (Coronary Atherosclerosis)
11/2011 - 07/2007
2Hemophilia B (Haemophilia B)
07/2011 - 12/2003
2Reperfusion Injury
04/2006 - 07/2002
2Infarction (Infarctions)
04/2006 - 07/2002
1Hypoxia (Hypoxemia)
01/2011
1Sickle Cell Anemia (Hemoglobin S Disease)
01/2011
1Vascular System Injuries
08/2010
1Thrombotic Thrombocytopenic Purpura
05/2010
1Myocardial Infarction
08/2009
1Vascular Diseases (Vascular Disease)
02/2008
1Acute Coronary Syndrome
12/2007
1Coronary Thrombosis
08/2007
1Neoplasms (Cancer)
07/2007
1Atherosclerosis
01/2007
1Myocardial Ischemia (Ischemic Heart Diseases)
04/2006
1Neointima
06/2004
1von Willebrand Diseases (von Willebrand's Disease)
07/2003
1Thrombocytopenia (Thrombopenia)
07/2003
1Ischemia
07/2002

Drug/Important Bio-Agent (IBA)

14P-SelectinIBA
04/2015 - 07/2002
8von Willebrand FactorIBA
04/2015 - 06/2002
5Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
04/2015 - 11/2002
5Factor VIII (Coagulation Factor VIII)IBA
01/2014 - 06/2002
4ARC 1779IBA
11/2011 - 12/2007
42- (4- chlorobenzyl)- 3- hydroxy- 7,8,9,10- tetrahydrobenzo(H)quinoline- 4- carboxylic acidIBA
02/2008 - 08/2005
4ImmunosorbentsIBA
09/2006 - 11/2002
4EnzymesIBA
09/2006 - 11/2002
3Enoxaparin (Lovenox)FDA LinkGeneric
04/2015 - 02/2008
3FibrinIBA
01/2014 - 08/2003
3Factor IX (Coagulation Factor IX)FDA LinkGeneric
07/2011 - 12/2003
3Thromboplastin (Tissue Factor)IBA
02/2008 - 11/2002
3Proteins (Proteins, Gene)FDA Link
08/2007 - 11/2003
3Glycoproteins (Glycoprotein)IBA
03/2006 - 07/2002
2Pharmaceutical PreparationsIBA
01/2014 - 04/2008
2ARC19499IBA
01/2014 - 05/2011
2lipoprotein-associated coagulation inhibitor (TFPI)IBA
01/2014 - 05/2011
2Clopidogrel (Plavix)FDA Link
11/2011 - 03/2006
2Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
08/2007 - 07/2003
2Peroxidase (Myeloperoxidase)IBA
07/2007 - 07/2002
2LigandsIBA
08/2005 - 07/2002
2AntibodiesIBA
08/2005 - 12/2003
2CytokinesIBA
07/2003 - 11/2002
1ARC5692IBA
04/2015
1ARC15105IBA
04/2015
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2011
1Blood Coagulation Factors (Coagulation Factor)IBA
07/2011
1ThrombinFDA Link
05/2011
1Carboxylic AcidsIBA
08/2010
1quinolineIBA
08/2010
1thiamine triphosphorate (TTP)IBA
05/2010
1Platelet Glycoprotein GPIb-IX Complex (Glycoprotein Ib)IBA
05/2010
1GadoliniumIBA
04/2010
1Plasminogen Activator Inhibitor 1IBA
04/2008
1tiplaxtininIBA
04/2008
1PSI-421IBA
02/2008
1quinoline-4-carboxylic acidIBA
02/2008
1enoxaparin sodiumFDA LinkGeneric
02/2008
1Fibrinolytic Agents (Antithrombotic Agents)IBA
12/2007
1guanylyl-(3'-5')-guanosineIBA
08/2007
1Platelet Membrane GlycoproteinsIBA
08/2007
1fibrin fragment D (D-dimer)IBA
03/2007
1rotigaptideIBA
04/2006
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2005
1InterleukinsIBA
08/2005
1Phenobarbital (Luminal)FDA Link
06/2004
1AntigensIBA
12/2003
1E-SelectinIBA
11/2003
1SelectinsIBA
11/2003
1Immunoglobulins (Immunoglobulin)IBA
08/2003
1Interleukin-11 (Interleukin 11)IBA
07/2003
1oprelvekin (Neumega)FDA Link
07/2003
1AnticoagulantsIBA
11/2002
1Hemostatics (Antihemorrhagics)IBA
06/2002
1recombinant factor VIII SQIBA
06/2002

Therapy/Procedure

4Therapeutics
11/2011 - 12/2003
3Ligation
08/2005 - 11/2002
1Stents
06/2004
1Intravenous Administration
12/2003
1Thrombolytic Therapy
11/2002